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Natural Toxins Registry: Plants and Mushrooms 

Background - Plants

Human exposures to plant toxins are relatively common.  In 2012, U.S. Poison Center’s received over 46,000 calls for exposures to plants. Despite this, research on the acute ingestion of these toxins in human populations is sparse, and is nearly exclusively case reports and small case series. 

The medical literature contains relatively little information on the clinical characteristics, demographics, and regionality of plant ingestions.  The purpose of ACMT’s Natural Toxins Registry – Plants is to gather detailed prospective information regarding ingestion amounts, method of confirmation, time to onset of symptoms, and clinical course of patients who ingest plants and are cared for by medical toxicologists.  The ultimate goal is to use the information gathered to develop appropriate guidance on the management of these exposures.

Authorship Guidelines for the Natural Toxins Registry - Plants

All medical toxicologists who contribute cases to the registry may be listed as members of the ACMT ToxIC Natural Toxin Registry study group, which will be credited in all publications stemming from the registry.

For reports on the entire registry, individually listed authors will include 1-2 investigators from the site contributing the most cases to the registry, and a single investigator from the next two sites with the highest case contribution.  For case series on individual types of plant exposures, individually listed authors will include 1-2 investigators from the site contributing the most cases of that type to the registry, as well as a single investigator from the next two sites with the highest case contribution.

In addition, all research must receive approval for a research proposal to the ACMT Research Committee.

All authors must meet the following requirements: 1) substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data; 2) drafting the article or revising it critically for important intellectual content; and 3) final approval of the version to be published.


Background - Mushrooms

Human exposures to mushrooms are relatively common and may lead to significant morbidity and rarely mortality.  In 2012, U.S. Poison Center’s received over 6000 calls for human exposures to mushrooms. Despite this, research on the acute ingestion of these toxins in human populations is relatively sparse. 

The medical literature contains relatively little detailed information on the clinical characteristics, demographics, and regionality of mushroom ingestions.  The purpose of ACMT’s Natural Toxins Registry – Mushrooms is to gather detailed prospective information regarding ingestion amounts, method of confirmation, time to onset of symptoms, and clinical course of patients who ingest mushrooms and are cared for by medical toxicologists.  The ultimate goal is to use the information gathered to develop appropriate guidance on the management of these exposures.

Authorship Guidelines for the Natural Toxins Registry - Mushrooms

All medical toxicologists who contribute cases to the registry may be listed as members of the ACMT ToxIC Natural Toxin Registry study group, which will be credited in all publications stemming from the registry.

For reports on the entire registry, individually listed authors will include 1-2 investigators from the site contributing the most cases to the registry and a single investigator from the next two sites with the highest case contribution.  For case series on individual types of mushroom exposures, individually listed authors will include 1-2 investigators from the site contributing the most cases of that type to the registry, as well as a single investigator from the next two sites with the highest case contribution.

In addition, all research must receive approval for a research proposal to the ACMT Research Committee.

All authors must meet the following requirements: 1) substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data; 2) drafting the article or revising it critically for important intellectual content; and 3) final approval of the version to be published.


Principal Investigator Contact Information

Robert G. Hendrickson, MD

Oregon Health and Science University, Portland, Oregon

hendriro@ohsu.edu  (503) 494-9495

Download the form for Natural Toxins: Plants 

Download the form for Natural Toxins: Mushrooms